You should take Levitra about one hour before sexual activity. The starting dose is than one in a day. These oral tablets can be taken with or without food. Should I avoid certain foods while taking Levitra? directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of. If you're taking standard Levitra tablets you can take these either with or without food, but be aware that if you take them with a high fat meal.